Job Opportunities
Postdoctoral Position, Department of Human Genetics, University of Chicago
The Molecular Genetics of CNS Development, Mental Retardation and Autism
A post-doctoral position is available immediately to study the molecular
genetics and biology of human cerebellar malformations. We are also
interested in cerebral cortex malformations, infantile forms of epilepsy
and autism. Together with Dr. William Dobyns, our group has just been
funded by the NIH to conduct a large scale array comparative genomic
hybridization (aCGH) analysis on DNA samples from 900 patients with
defined brain malformations to identify causative duplications or
deletions, and we have additional funding for aCGH studies in autism as
well. We expect novel and exciting data to result from this work. Over
the past six months, our pilot analysis of just 20 patients has
identified 3 novel causative genomic copy number variants (CNV) and we
have already generated one transgenic mouse model replicating the
corresponding human phenotype - in this case a duplication. This allowed
us to confirm the causative gene, a novel player in brain development.
Techniques include array comparative genomic hybridization, microarray
expression profiling, bioinformatics, mouse genetic and phenotypic
analysis and finally, chick and zebrafish embryonic assays. We are
interested in both defining novel brain developmental mechanisms in
addition to contributing to improved clinical diagnosis in children with
developmental handicaps.
For a partial list of lab research interests, see website:
http://www.genes.uchicago.edu/.
This is an NIH-funded post-doctoral position within the Developmental
Disabilities Research Center - Chicago, a research center within the
Department of Human Genetics at the University of Chicago. We also have
private donor money in hand for the first year.
Highly motivated individuals with an interest in genetics and
developmental neurobiology are encouraged to apply. Experience in
molecular biology is required, experience with mouse models is a plus.
Enthusiasm and independence are essential. Interested candidates should
send a letter stating interests, curriculum vitae and list of
publications, along with the names and contact information of three
references via e-mail to:
Kathleen Millen, Ph.D
Associate Professor
Departments of Human Genetics and Neurology
kmillen@genetics.uchicago.edu
The University of Chicago is an Equal Opportunity/Affirmative Action Employer.
Research Associate (Assistant Professor), University of Chicago
The University of Chicago's Department of Human Genetics is seeking a
qualified applicant for a full time Research Associate (Asst. Prof)
position to join a program investigating the genetic and genomic basis
of human cerebellar malformations, mental retardation and developmental
delay using model organisms.
We are seeking a mature, motivated candidate with extensive background
and skill in molecular genetic methods including, positional cloning,
DNA and RNA analysis including quantitative RT-PCR, RNA in situ
analysis, immunohistochemistry, advanced microscopy, mouse embryology
and husbandry, chick in ovo electroporation and CNS explant cultures.
Qualifications: Ph.D. in biology or a related field with at least 5
years post-doctoral experience is required. Expertise in both mouse and
chick embryology together with use of genome database resources is
essential. The applicant must be able to design and conduct experiments
independently, supervise laboratory personnel, prepare and present their
work at national meetings, and write scientific manuscripts and grant
applications.
Interested applicants should apply online at:
jobopportunities.uchicago.edu/applicants/Central?quickFind=198553.
Applicants must attach electronic copies of a curriculum vitae, a short
summary of research plans and the names and contact information for 3
references.
The University of Chicago is an Affirmative Action/Equal Opportunity
Employer
Director Caltech Genomics Facility - CIT14483MM
Caltech seeks genome scientist to direct its genomics facility - the
Millard and Muriel Jacobs Genetics and Genomics Laboratory.
The purpose of the Facility is to provide cutting-edge technology in the
area of functional genomics, with current emphasis on next-generation
sequencing and on various microarray-based technologies. Working
interactions with many research user groups in Biology, Chemistry,
GeoBiology, and Engineering are central to the Facility mission. We
expect the Facility Director to direct technical staff and to play a
leadership role in developing, testing, and introducing new technologies
that will define future Facility capabilities, as well as in the
integration and collaboration in Bioinformatics. The Facility Director
is also responsible for managing the financial resources of the
Laboratory, writing papers, presenting the work and writing the
pertinent section for the Division's Annual Report.
Background required is a doctoral degree and postdoctoral research
experience in an appropriate area of genomics. Experience in
next-generation sequencing and/or bioinformatics is a plus.
To be considered for this outstanding opportunity, please visit our web
site and submit your resume at the following link:
http://www2.recruitingcenter.net/clients/CalTech/publicjobs/controller.cfm?jbaction=JobProfile&Job_Id=14483&esid=az
Please direct questions or concerns to:
Ms. Susan Ruffins, Office of the Director Beckman Institute, Caltech,
Pasadena, CA 91125, 626-395-2788, str@caltech.edu
Caltech is an Affirmative Action/Equal Opportunity Employer. Women,
Minorities, Veterans and Disabled Persons are encouraged to apply.
GENOMICS SPECIALIST I/II – KW21560, Fred Hutchinson Cancer Research Center
About Us:
Fred Hutchinson Cancer Research Center, home of three Nobel laureates,
is an independent, nonprofit research institution dedicated to the
development and advancement of biomedical research to eliminate cancer
and other potentially fatal diseases. Recognized internationally for its
pioneering work in bone-marrow transplantation, the Center’s four
scientific divisions collaborate to form a unique environment for
conducting basic and applied science. The Hutchinson Center, in
collaboration with its clinical and research partners, the University of
Washington and Children’s Hospital and Regional Medical Center, is the
only National Cancer Institute-designated comprehensive cancer center in
the Pacific Northwest. Join us and make a difference.
Job Description:
The Genomics Resource consists of two core facilities that provide
support for sequencing, genotyping, and microarray activities throughout
the Center. This individual will work under the direct supervision of
the Genomics Resource Supervisor. Key areas of activity will include:
• Support activities in the Genomics Resource’s DNA Array lab.
• Provide back-up support services in the Genetic Analysis Lab,
including the operation of ABI sequencing instrumentation.
• Provide back-up training and support on real-time PCR instrumentation.
• Perform other responsibilities as required.
The ideal candidate will possess the following qualifications:
Must have an undergraduate degree in a biological discipline, plus a
minimum of at least 2 years of professional laboratory experience.
We seek a mature, professional individual with a proven track record in
a laboratory setting. Expertise in molecular biology techniques is
essential, and a working knowledge and comfort with microarray and
sequencing technologies is desired. Proficiency working with computers
and navigating software applications is essential. Strong interpersonal
and organizational skills are also required, as is the ability to work
in a highly independent environment.
Compensation: Salary DOE+ excellent benefits; full-time position.
Date opened: February 19, 2008
Job #KW-21560
Apply online: www.fhcrc.org
The Fred Hutchinson Cancer Research Center and The Seattle Cancer Care Alliance are equal opportunity employers, committed to workforce diversity.
Job Description for Senior Scientist for Myers Lab ENCODE Project
Dr. Richard M. Myers' laboratory at the HudsonAlpha Institute for
Biotechnology seeks an ENCODE Senior Scientist to help manage the
research in Myers Laboratory. The applicant will help lead the
experimental and computational work in a very large effort to identify
and characterize all the functional elements in the human genome, as
part of the international ENCODE (ENCyclopedia of DNA Elements)
Consortium. This high profile project is part of a consortium of seven
laboratories located around the U.S. and in the United Kingdom, and Dr.
Myers' group has been funded to perform the largest project in the
consortium. The candidate will help coordinate the efforts a group of
four technicians and one or more computer scientists, working closely
with the Principal Investigator and several graduate students and
Postdoctoral Fellows in the lab to do both computational and large-scale
experimental work to accomplish the goal of thoroughly studying and
annotating the human genome.
A Ph.D. in genomics, genetics, biochemistry, molecular biology, or a
related field is required, as well as a successful research experience
as a Postdoctoral Fellow. A demonstrated record of scientific
accomplishments, leadership, and experience supervising research
assistants is strongly preferred. Extensive molecular biology
experience with proven ability to work with large data sets is
necessary. An ideal background includes thorough knowledge of
eukaryotic gene expression and previous experience with the experimental
techniques commonly used. Another requirement is computational skills
for inputting, analyzing and distributing large data sets along with
abilities in high-level analysis for integrating large, diverse
datasets; this includes an ability to do mid-level programming and
database construction as well as a strong knowledge of and experience in
statistical analyses. The successful candidate will be an individual
with exceptional organizational, writing and communication abilities.
HudsonAlpha Institute for Biotechnology was founded in 2005 as
non-profit facility with the mission to use biotechnology and basic
biological research to make important discoveries, improve human health,
stimulate economic development and inspire young people to seek careers
in science. Located in Cummings Research Park in Huntsville, Alabama,
one of the world’s leading science and technology business parks, the
four-story, 270,000 square foot building will house up to 700 employees
and will fully open its operations in March 2008. The facility contains
state-of-the-art laboratories for biological research and development in
the areas of genomics, genetics and personalized medicine. In addition,
space and resources are allocated for high school, college-level and
adult educational outreach and training programs. Dr. Richard Myers has
accepted the job as Scientific Director of the institute and will soon
leave his current position as Chair of the Department of Genetics at
Stanford University School of Medicine. Dr. Myers' lab conducts
research in human genetics and genomics and has participated in the
international ENCODE Project Consortium since its beginning four years
ago to map and understand the activities of all the functional elements
in the human genome.
For more information on the institute, please see www.hudsonalpha.org.
Interested in other job opportunities?
Genes & Development,
Protein Science,
RNA
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