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Supplementary Material

Supplementary material related to the following articles is available online:

From the Current Issue: 18 (7); [Table of Contents]

Chaim Linhart, Yonit Halperin, and Ron Shamir
Transcription factor and microRNA motif discovery: The Amadeus platform and a compendium of metazoan target sets
Genome Res. 2008; 18(7): 1180-1189 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Vijay K. Tiwari, Leslie Cope, Kelly M. McGarvey, Joyce E. Ohm, and Stephen B. Baylin
A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations
Genome Res. 2008; 18(7): 1171-1179 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Yao-Ting Huang, Feng-Chi Chen, Chiuan-Jung Chen, Hsin-Liang Chen, and Trees-Juen Chuang
Identification and analysis of ancestral hominoid transcriptome inferred from cross-species transcript and processed pseudogene comparisons
Genome Res. 2008; 18(7): 1163-1170 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Ivan Iossifov, Tian Zheng, Miron Baron, T. Conrad Gilliam, and Andrey Rzhetsky
Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network
Genome Res. 2008; 18(7): 1150-1162 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Wei Chen, Vera Kalscheuer, Andreas Tzschach, Corinna Menzel, Reinhard Ullmann, Marcel Holger Schulz, Fikret Erdogan, Na Li, Zofia Kijas, Ger Arkesteijn, Isidora Lopez Pajares, Margret Goetz-Sothmann, Uwe Heinrich, Imma Rost, Andreas Dufke, Ute Grasshoff, Birgitta Glaeser, Martin Vingron, and H. Hilger Ropers
Mapping translocation breakpoints by next-generation sequencing
Genome Res. 2008; 18(7): 1143-1149 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Nitin Gupta, Jamal Benhamida, Vipul Bhargava, Daniel Goodman, Elisabeth Kain, Ian Kerman, Ngan Nguyen, Noah Ollikainen, Jesse Rodriguez, Jian Wang, Mary S. Lipton, Margaret Romine, Vineet Bafna, Richard D. Smith, and Pavel A. Pevzner
Comparative proteogenomics: Combining mass spectrometry and comparative genomics to analyze multiple genomes
Genome Res. 2008; 18(7): 1133-1142 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Jr-Kai Yu, Daniel Meulemans, Sonja J. McKeown, and Marianne Bronner-Fraser
Insights from the amphioxus genome on the origin of vertebrate neural crest
Genome Res. 2008; 18(7): 1127-1132 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Shengfeng Huang, Shaochun Yuan, Lei Guo, Yanhong Yu, Jun Li, Tao Wu, Tong Liu, Manyi Yang, Kui Wu, Huiling Liu, Jin Ge, Yingcai Yu, Huiqing Huang, Meiling Dong, Cuiling Yu, Shangwu Chen, and Anlong Xu
Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity
Genome Res. 2008; 18(7): 1112-1126 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Linda Z. Holland, Ricard Albalat, Kaoru Azumi, Èlia Benito-Gutiérrez, Matthew J. Blow, Marianne Bronner-Fraser, Frederic Brunet, Thomas Butts, Simona Candiani, Larry J. Dishaw, David E.K. Ferrier, Jordi Garcia-Fernàndez, Jeremy J. Gibson-Brown, Carmela Gissi, Adam Godzik, Finn Hallböök, Dan Hirose, Kazuyoshi Hosomichi, Tetsuro Ikuta, Hidetoshi Inoko, Masanori Kasahara, Jun Kasamatsu, Takeshi Kawashima, Ayuko Kimura, Masaaki Kobayashi, Zbynek Kozmik, Kaoru Kubokawa, Vincent Laudet, Gary W. Litman, Alice C. McHardy, Daniel Meulemans, Masaru Nonaka, Robert P. Olinski, Zeev Pancer, Len A. Pennacchio, Mario Pestarino, Jonathan P. Rast, Isidore Rigoutsos, Marc Robinson-Rechavi, Graeme Roch, Hidetoshi Saiga, Yasunori Sasakura, Masanobu Satake, Yutaka Satou, Michael Schubert, Nancy Sherwood, Takashi Shiina, Naohito Takatori, Javier Tello, Pavel Vopalensky, Shuichi Wada, Anlong Xu, Yuzhen Ye, Keita Yoshida, Fumiko Yoshizaki, Jr-Kai Yu, Qing Zhang, Christian M. Zmasek, Pieter J. de Jong, Kazutoyo Osoegawa, Nicholas H. Putnam, Daniel S. Rokhsar, Noriyuki Satoh, and Peter W.H. Holland
The amphioxus genome illuminates vertebrate origins and cephalochordate biology
Genome Res. 2008; 18(7): 1100-1111 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Gabriel Musso, Michael Costanzo, ManQin Huangfu, Andrew M. Smith, Jadine Paw, Bryan-Joseph San Luis, Charles Boone, Guri Giaever, Corey Nislow, Andrew Emili, and Zhaolei Zhang
The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast
Genome Res. 2008; 18(7): 1092-1099 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Itay Tirosh and Naama Barkai
Two strategies for gene regulation by promoter nucleosomes
Genome Res. 2008; 18(7): 1084-1091 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Travis N. Mavrich, Ilya P. Ioshikhes, Bryan J. Venters, Cizhong Jiang, Lynn P. Tomsho, Ji Qi, Stephan C. Schuster, Istvan Albert, and B. Franklin Pugh
A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome
Genome Res. 2008; 18(7): 1073-1083 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Jun S. Song, Xingkun Liu, X. Shirley Liu, and Xiangwei He
A high-resolution map of nucleosome positioning on a fission yeast centromere
Genome Res. 2008; 18(7): 1064-1072 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Anton Valouev, Jeffrey Ichikawa, Thaisan Tonthat, Jeremy Stuart, Swati Ranade, Heather Peckham, Kathy Zeng, Joel A. Malek, Gina Costa, Kevin McKernan, Arend Sidow, Andrew Fire, and Steven M. Johnson
A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning
Genome Res. 2008; 18(7): 1051-1063 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Elizabeth A. Grice, Heidi H. Kong, Gabriel Renaud, Alice C. Young, NISC Comparative Sequencing Program, Gerard G. Bouffard, Robert W. Blakesley, Tyra G. Wolfsberg, Maria L. Turner, and Julia A. Segre
A diversity profile of the human skin microbiota
Genome Res. 2008; 18(7): 1043-1050 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Stefan Kirsch, Claudia Münch, Zhaoshi Jiang, Ze Cheng, Lin Chen, Christiane Batz, Evan E. Eichler, and Werner Schempp
Evolutionary dynamics of segmental duplications from human Y-chromosomal euchromatin/heterochromatin transition regions
Genome Res. 2008; 18(7): 1030-1042 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Ines Hellmann, Yuan Mang, Zhiping Gu, Peter Li, Francisco M. de la Vega, Andrew G. Clark, and Rasmus Nielsen
Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals
Genome Res. 2008; 18(7): 1020-1029 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

From Past Issues:

Matthew M. Hill, Karl W. Broman, Elia Stupka, William C. Smith, Di Jiang, and Arend Sidow
The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution
Genome Res. 2008; 0(2008): gr.078576.108v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Zhaoshi Jiang, Robert Hubley, Arian Smit, and Evan E. Eichler
DupMasker: A tool for annotating primate segmental duplications
Genome Res. 2008; 0(2008): gr.078477.108v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

David Monk, Alexandre Wagschal, Philippe Arnaud, Pari Sima-Muller, Layla Parker-Katiraee, Déborah Bourc’his, Stephen W. Scherer, Robert Feil, Philip Stanier, and Gudrun E. Moore
Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing
Genome Res. 2008; 0(2008): gr.077115.108v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Qian-Ru Li, Anne-Ruxandra Carvunis, Haiyuan Yu, Jing-Dong J. Han, Quan Zhong, Nicolas Simonis, Stanley Tam, Tong Hao, Niels J. Klitgord, Denis Dupuy, Danny Mou, Ilan Wapinski, Aviv Regev, David E. Hill, Michael E. Cusick, and Marc Vidal
Revisiting the Saccharomyces cerevisiae predicted ORFeome
Genome Res. 2008; 0(2008): gr.076661.108v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Paz Polak and Peter F. Arndt
Transcription induces strand-specific mutations at the 5' end of human genes
Genome Res. 2008; 0(2008): gr.076570.108v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Matthew J. Blow, Tao Zhang, Tanja Woyke, Camilla F. Speller, Andrei Krivoshapkin, Dongya Y. Yang, Anatoly Derevianko, and Edward M. Rubin
Identification of ancient remains through genomic sequencing
Genome Res. 2008; 0(2008): gr.076091.108v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Brian P. Chadwick
DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts
Genome Res. 2008; 0(2008): gr.075713.107v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Jeffrey D. Wall, Murray P. Cox, Fernando L. Mendez, August Woerner, Tesa Severson, and Michael F. Hammer
A novel DNA sequence database for analyzing human demographic history
Genome Res. 2008; 0(2008): gr.075630.107v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Isabel Aznarez, Yoseph Barash, Ofer Shai, David He, Julian Zielenski, Lap-Chee Tsui, John Parkinson, Brendan J. Frey, Johanna M. Rommens, and Benjamin J. Blencowe
A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation
Genome Res. 2008; 0(2008): gr.073155.107v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Hong Yu, Shanshan Zhu, Bing Zhou, Huiling Xue, and Jing-Dong J. Han
Inferring causal relationships among different histone modifications and gene expression
Genome Res. 2008; 0(2008): gr.073080.107v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Dan Xie, Jun Cai, Na-Yu Chia, Huck H. Ng, and Sheng Zhong
Cross-species de novo identification of cis-regulatory modules with GibbsModule: Application to gene regulation in embryonic stem cells
Genome Res. 2008; 0(2008): gr.072769.107v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Belinda J Norris and Vicki A Whan
A gene duplication affecting expression of the ovine ASIP gene is responsible for white and black sheep
Genome Res. 2008; 0(2008): gr.072090.107v2 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Paul F. O’Reilly, Ewan Birney, and David J. Balding
Confounding between recombination and selection, and the Ped/Pop method for detecting selection
Genome Res. 2008; 0(2008): gr.067181.107v1 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Alexander Stark, Pouya Kheradpour, Sushmita Roy, and Manolis Kellis
Reliable prediction of regulator targets using 12 Drosophila genomes
Genome Res. 2007; 0(2007): gr.7090407v1 [Abstract]  
Article supplement(s): [Correction] [Drosophila 12 Genomes] [Supplemental Research Data]

Martin Beye, Irene Gattermeier, Martin Hasselmann, Tanja Gempe, Morten Schioett, John F. Baines, David Schlipalius, Florence Mougel, Christine Emore, Olav Rueppell, Anu Sirviö, Ernesto Guzmán-Novoa, Greg Hunt, Michel Solignac, and Robert E. Page Jr.
Exceptionally high levels of recombination across the honey bee genome
Genome Res. 2006; 0(2006): gr.5680406v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Christine G. Elsik, Kim C. Worley, Lan Zhang, Natalia V. Milshina, Huaiyang Jiang, Justin T. Reese, Kevin L. Childs, Anand Venkatraman, C. Michael Dickens, George M. Weinstock, and Richard A. Gibbs
Community annotation: Procedures, protocols, and supporting tools
Genome Res. 2006; 0(2006): gr.5580606v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Joël Savard, Diethard Tautz, Stephen Richards, George M. Weinstock, Richard A. Gibbs, John H. Werren, Hervé Tettelin, and Martin J. Lercher
Phylogenomic analysis reveals bees and wasps (Hymenoptera) at the base of the radiation of Holometabolous insects
Genome Res. 2006; 0(2006): gr.5204306v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Peter K. Dearden, Megan J. Wilson, Lisha Sablan, Peter W. Osborne, Melanie Havler, Euan McNaughton, Kiyoshi Kimura, Natalia V. Milshina, Martin Hasselmann, Tanja Gempe, Morten Schioett, Susan J. Brown, Christine G. Elsik, Peter W.H. Holland, Tatsuhiko Kadowaki, and Martin Beye
Patterns of conservation and change in honey bee developmental genes
Genome Res. 2006; 0(2006): gr.5108606v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Elad B. Rubin, Yair Shemesh, Mira Cohen, Sharona Elgavish, Hugh M. Robertson, and Guy Bloch
Molecular and phylogenetic analyses reveal mammalian-like clockwork in the honey bee (Apis mellifera) and shed new light on the molecular evolution of the circadian clock
Genome Res. 2006; 0(2006): gr.5094806v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Hugh M. Robertson and Karl H.J. Gordon
Canonical TTAGG-repeat telomeres and telomerase in the honey bee Apis mellifera
Genome Res. 2006; 0(2006): gr.5085606v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Sylvain Forêt and Ryszard Maleszka
Function and evolution of a gene family encoding odorant binding-like proteins in a social insect, the honey bee (Apis mellifera)
Genome Res. 2006; 0(2006): gr.5075706v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Hugh M. Robertson and Kevin W. Wanner
The chemoreceptor superfamily in the honey bee Apis mellifera: Expansion of the odorant, but not gustatory, receptor family
Genome Res. 2006; 0(2006): gr.5057506v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Tara D. Sutherland, Peter M. Campbell, Sarah Weisman, Holly E. Trueman, Alagacone Sriskantha, Wolfgang J. Wanjura, and Victoria S. Haritos
A highly divergent gene cluster in honey bees encodes a novel silk family
Genome Res. 2006; 0(2006): gr.5052606v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Mark David Drapeau, Stefan Albert, Robert Kucharski, Carsten Prusko, and Ryszard Maleszka
Evolution of the Yellow/Major Royal Jelly Protein family and the emergence of social behaviorin honey bees
Genome Res. 2006; 0(2006): gr.5012006v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Noam Kaplan and Michal Linial
ProtoBee: Hierarchical classification and annotation of the honey bee proteome
Genome Res. 2006; 0(2006): gr.4916306v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus]

Soochin Cho, Zachary Y. Huang, Daniel R. Green, Deborah R. Smith, and Jianzhi Zhang
Evolution of the complementary sex-determination gene of honey bees: Balancing selectionand trans-species polymorphisms
Genome Res. 2006; 0(2006): gr.4695306v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplementary Research Data]

Andrew K. Jones, Valerie Raymond-Delpech, Steeve H. Thany, Monique Gauthier, and David B. Sattelle
The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera
Genome Res. 2006; 0(2006): gr.4549206v1 [Abstract]  
Article supplement(s): [Honey Bee Genome Focus] [Supplemental Research Data]

Astrid Lægreid, Torgeir R. Hvidsten, Herman Midelfart, Jan Komorowski, and Arne K. Sandvik
Predicting Gene Ontology Biological Process From Temporal Gene Expression Patterns
Genome Res. 2003; 0(2003): GR-11445Rv1 [Abstract]  
Article supplement(s): [Supplemental Research Data] [Supplemental Research Data]

James W. Thomas, Mary G. Schueler, Tyrone J. Summers, Robert W. Blakesley, Jennifer C. McDowell, Pamela J. Thomas, Jacquelyn R. Idol, Valerie V.B. Maduro, Shih-Queen Lee-Lin, Jeffrey W. Touchman, Gerard G. Bouffard, Stephen M. Beckstrom-Sternberg, NISC Comparative Sequencing Program, and Eric D. Green
Pericentromeric Duplications in the Laboratory Mouse
Genome Res. 2002; 0(2002): GR-7914Rv1 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Pavel Pevzner and Glenn Tesler
Genome Rearrangements in Mammalian Evolution: Lessons From Human and Mouse Genomes
Genome Res. 2002; 0(2002): GR-7575Rv1 [Abstract]  
Article supplement(s): [Supplemental Research Data]

John E. Collins, Melanie E. Goward, Charlotte G. Cole, Luc J. Smink, Elizabeth J. Huckle, Sarah Knowles, Jacqueline M. Bye, David M. Beare, and Ian Dunham
Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22
Genome Res. 2002; 0(2002): GR-6957Rv1 [Abstract]  
Article supplement(s): [Supplemental Research Data]

Maido Remm and Erik Sonnhammer
Classification of Transmembrane Protein Families in the Caenorhabditis elegans Genome and Identification of Human Orthologs
Genome Res. 2000; 0(2000): GR-1491Rv1-99999 [Abstract] [Full Text]  
Article supplement(s): [ Supplemental Research Data]

Jürgen Schmitz, Anja Zemann, Gennady Churakov, Heiner Kuhl, Frank Grützner, Richard Reinhardt, and Jürgen Brosius
Retroposed SNOfall—A mammalian-wide comparison of platypus snoRNAs
Genome Res. 2008; 18(6): 1005-1010 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Elizabeth P. Murchison, Pouya Kheradpour, Ravi Sachidanandam, Carly Smith, Emily Hodges, Zhenyu Xuan, Manolis Kellis, Frank Grützner, Alexander Stark, and Gregory J. Hannon
Conservation of small RNA pathways in platypus
Genome Res. 2008; 18(6): 995-1004 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Camilla M. Whittington, Anthony T. Papenfuss, Paramjit Bansal, Allan M. Torres, Emily S.W. Wong, Janine E. Deakin, Tina Graves, Amber Alsop, Kyriena Schatzkamer, Colin Kremitzki, Chris P. Ponting, Peter Temple-Smith, Wesley C. Warren, Philip W. Kuchel, and Katherine Belov
Defensins and the convergent evolution of platypus and reptile venom genes
Genome Res. 2008; 18(6): 986-994 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Jae-Il Park, Jenia Semyonov, Chia Lin Chang, Wei Yi, Wesley Warren, and Sheau Yu Teddy Hsu
Origin of INSL3-mediated testicular descent in therian mammals
Genome Res. 2008; 18(6): 974-985 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Evgeny A. Glazov, Pauline A. Cottee, Wesley C. Barris, Robert J. Moore, Brian P. Dalrymple, and Mark L. Tizard
A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach
Genome Res. 2008; 18(6): 957-964 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Qingwu Yang and Sing-Hoi Sze
Large-scale analysis of gene clustering in bacteria
Genome Res. 2008; 18(6): 949-956 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Giusy Della Gatta, Mukesh Bansal, Alberto Ambesi-Impiombato, Dario Antonini, Caterina Missero, and Diego di Bernardo
Direct targets of the TRP63 transcription factor revealed by a combination of gene expression profiling and reverse engineering
Genome Res. 2008; 18(6): 939-948 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Mahesh Yaragatti, Claudio Basilico, and Lisa Dailey
Identification of active transcriptional regulatory modules by the functional assay of DNA from nucleosome-free regions
Genome Res. 2008; 18(6): 930-938 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Georg Zeller, Richard M. Clark, Korbinian Schneeberger, Anja Bohlen, Detlef Weigel, and Gunnar Rätsch
Detecting polymorphic regions in Arabidopsis thaliana with resequencing microarrays
Genome Res. 2008; 18(6): 918-929 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Byung-Kwan Cho, Eric M. Knight, Christian L. Barrett, and Bernhard Ø. Palsson
Genome-wide analysis of Fis binding in Escherichia coli indicates a causative role for A-/AT-tracts
Genome Res. 2008; 18(6): 900-910 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Pontus Larsson, Andrea Hinas, David H. Ardell, Leif A. Kirsebom, Anders Virtanen, and Fredrik Söderbom
De novo search for non-coding RNA genes in the AT-rich genome of Dictyostelium discoideum: Performance of Markov-dependent genome feature scoring
Genome Res. 2008; 18(6): 888-899 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Mikael Brandström and Hans Ellegren
Genome-wide analysis of microsatellite polymorphism in chicken circumventing the ascertainment bias
Genome Res. 2008; 18(6): 881-887 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Keiko Akagi, Jingfeng Li, Robert M. Stephens, Natalia Volfovsky, and David E. Symer
Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition
Genome Res. 2008; 18(6): 869-880 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Ei-suke Saito, Vincent W. Keng, Junji Takeda, and Kyoji Horie
Translation from nonautonomous type IAP retrotransposon is a critical determinant of transposition activity: Implication for retrotransposon-mediated genome evolution
Genome Res. 2008; 18(6): 859-868 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Marijke Bauters, Hilde Van Esch, Michael J. Friez, Odile Boespflug-Tanguy, Martin Zenker, Angela M. Vianna-Morgante, Carla Rosenberg, Jaakko Ignatius, Martine Raynaud, Karen Hollanders, Karen Govaerts, Kris Vandenreijt, Florence Niel, Pierre Blanc, Roger E. Stevenson, Jean-Pierre Fryns, Peter Marynen, Charles E. Schwartz, and Guy Froyen
Nonrecurrent MECP2 duplications mediated by genomic architecture-driven DNA breaks and break-induced replication repair
Genome Res. 2008; 18(6): 847-858 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Tatiana M. Karafet, Fernando L. Mendez, Monica B. Meilerman, Peter A. Underhill, Stephen L. Zegura, and Michael F. Hammer
New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree
Genome Res. 2008; 18(5): 830-838 [Abstract] [Full Text]  
Article supplement(s): [Y-Chromosome Phylogenetic Tree Poster] [Supplemental Research Data]

Daniel R. Zerbino and Ewan Birney
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs
Genome Res. 2008; 18(5): 821-829 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Jonathan Butler, Iain MacCallum, Michael Kleber, Ilya A. Shlyakhter, Matthew K. Belmonte, Eric S. Lander, Chad Nusbaum, and David B. Jaffe
ALLPATHS: De novo assembly of whole-genome shotgun microreads
Genome Res. 2008; 18(5): 810-820 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

David Hernandez, Patrice François, Laurent Farinelli, Magne Østerås, and Jacques Schrenzel
De novo bacterial genome sequencing: Millions of very short reads assembled on a desktop computer
Genome Res. 2008; 18(5): 802-809 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Yih-Jyh Shann, Ching Cheng, Chun-Hui Chiao, Dow-Tien Chen, Pei-Hsin Li, and Ming-Ta Hsu
Genome-wide mapping and characterization of hypomethylated sites in human tissues and breast cancer cell lines
Genome Res. 2008; 18(5): 791-801 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Rafael A. Irizarry, Christine Ladd-Acosta, Benilton Carvalho, Hao Wu, Sheri A. Brandenburg, Jeffrey A. Jeddeloh, Bo Wen, and Andrew P. Feinberg
Comprehensive high-throughput arrays for relative methylation (CHARM)
Genome Res. 2008; 18(5): 780-790 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Hans T. Bjornsson, Thomas J. Albert, Christine M. Ladd-Acosta, Roland D. Green, Michael A. Rongione, Christina M. Middle, Rafael A. Irizarry, Karl W. Broman, and Andrew P. Feinberg
SNP-specific array-based allele-specific expression analysis
Genome Res. 2008; 18(5): 771-779 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

William Brockman, Pablo Alvarez, Sarah Young, Manuel Garber, Georgia Giannoukos, William L. Lee, Carsten Russ, Eric S. Lander, Chad Nusbaum, and David B. Jaffe
Quality scores and SNP detection in sequencing-by-synthesis systems
Genome Res. 2008; 18(5): 763-770 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Jun Chen, Yeong C. Kim, Yong-Chul Jung, Zhenyu Xuan, Geoff Dworkin, Yanming Zhang, Michael Q. Zhang, and San Ming Wang
Scanning the human genome at kilobase resolution
Genome Res. 2008; 18(5): 751-762 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Bernard La Scola, Khalid Elkarkouri, Wenjun Li, Tara Wahab, Ghislain Fournous, Jean-Marc Rolain, Silpak Biswas, Michel Drancourt, Catherine Robert, Stéphane Audic, Sven Löfdahl, and Didier Raoult
Rapid comparative genomic analysis for clinical microbiology: The Francisella tularensis paradigm
Genome Res. 2008; 18(5): 742-750 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Timothy P. Stinear, Torsten Seemann, Paul F. Harrison, Grant A. Jenkin, John K. Davies, Paul D.R. Johnson, Zahra Abdellah, Claire Arrowsmith, Tracey Chillingworth, Carol Churcher, Kay Clarke, Ann Cronin, Paul Davis, Ian Goodhead, Nancy Holroyd, Kay Jagels, Angela Lord, Sharon Moule, Karen Mungall, Halina Norbertczak, Michael A. Quail, Ester Rabbinowitsch, Danielle Walker, Brian White, Sally Whitehead, Pamela L.C. Small, Roland Brosch, Lalita Ramakrishnan, Michael A. Fischbach, Julian Parkhill, and Stewart T. Cole
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
Genome Res. 2008; 18(5): 729-741 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

David A. Ray, Cedric Feschotte, Heidi J.T. Pagan, Jeremy D. Smith, Ellen J. Pritham, Peter Arensburger, Peter W. Atkinson, and Nancy L. Craig
Multiple waves of recent DNA transposon activity in the bat, Myotis lucifugus
Genome Res. 2008; 18(5): 717-728 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Mark P. Keller, YounJeong Choi, Ping Wang, Dawn Belt Davis, Mary E. Rabaglia, Angie T. Oler, Donald S. Stapleton, Carmen Argmann, Kathy L. Schueler, Steve Edwards, H. Adam Steinberg, Elias Chaibub Neto, Robert Kleinhanz, Scott Turner, Marc K. Hellerstein, Eric E. Schadt, Brian S. Yandell, Christina Kendziorski, and Alan D. Attie
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility
Genome Res. 2008; 18(5): 706-716 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Kirstin Knox and Julie C. Baker
Genomic evolution of the placenta using co-option and duplication and divergence
Genome Res. 2008; 18(5): 695-705 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Ivon Cuscó, Roser Corominas, Mònica Bayés, Raquel Flores, Núria Rivera-Brugués, Victoria Campuzano, and Luis A. Pérez-Jurado
Copy number variation at the 7q11.23 segmental duplications is a susceptibility factor for the Williams-Beuren syndrome deletion
Genome Res. 2008; 18(5): 683-694 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]


Genome Res. 2008; 18(5): 683-838  
Issue supplement(s): [This issue is sponsored by Roche Applied Science] [Y-Chromosome Phylogenetic Tree Poster]

Dongliang Ge, Kunlin Zhang, Anna C. Need, Olivier Martin, Jacques Fellay, Thomas J. Urban, Amalio Telenti, and David B. Goldstein
WGAViewer: Software for genomic annotation of whole genome association studies
Genome Res. 2008; 18(4): 640-643 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Dean Tantin, Matthew Gemberling, Catherine Callister, and William Fairbrother
High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes
Genome Res. 2008; 18(4): 631-639 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

K. Mark Bushell, Christian Söllner, Benjamin Schuster-Boeckler, Alex Bateman, and Gavin J. Wright
Large-scale screening for novel low-affinity extracellular protein interactions
Genome Res. 2008; 18(4): 622-630 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Ryan D. Morin, Michael D. O’Connor, Malachi Griffith, Florian Kuchenbauer, Allen Delaney, Anna-Liisa Prabhu, Yongjun Zhao, Helen McDonald, Thomas Zeng, Martin Hirst, Connie J. Eaves, and Marco A. Marra
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
Genome Res. 2008; 18(4): 610-621 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

David Ribet, Francis Harper, Anne Dupressoir, Marie Dewannieux, Gérard Pierron, and Thierry Heidmann
An infectious progenitor for the murine IAP retrotransposon: Emergence of an intracellular genetic parasite from an ancient retrovirus
Genome Res. 2008; 18(4): 597-609 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Ryan D. Morin, Gozde Aksay, Elena Dolgosheina, H. Alexander Ebhardt, Vincent Magrini, Elaine R. Mardis, S. Cenk Sahinalp, and Peter J. Unrau
Comparative analysis of the small RNA transcriptomes of Pinus contorta and Oryza sativa
Genome Res. 2008; 18(4): 571-584 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Erica D. Smith, Mitsuhiro Tsuchiya, Lindsay A. Fox, Nick Dang, Di Hu, Emily O. Kerr, Elijah D. Johnston, Bie N. Tchao, Diana N. Pak, K. Linnea Welton, Daniel E.L. Promislow, James H. Thomas, Matt Kaeberlein, and Brian K. Kennedy
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species
Genome Res. 2008; 18(4): 564-570 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Catarina D. Campbell, Andrew Kirby, James Nemesh, Mark J. Daly, and Joel N. Hirschhorn
A survey of allelic imbalance in F1 mice
Genome Res. 2008; 18(4): 555-563 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Kevin Bullaughey, Molly Przeworski, and Graham Coop
No effect of recombination on the efficacy of natural selection in primates
Genome Res. 2008; 18(4): 544-554 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Shengdong Ke, Xiang H.-F. Zhang, and Lawrence A. Chasin
Positive selection acting on splicing motifs reflects compensatory evolution
Genome Res. 2008; 18(4): 533-543 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Vitalina M. Komashko, Luis G. Acevedo, Sharon L. Squazzo, Sushma S. Iyengar, Alina Rabinovich, Henriette O’Geen, Roland Green, and Peggy J. Farnham
Using ChIP-chip technology to reveal common principles of transcriptional repression in normal and cancer cells
Genome Res. 2008; 18(4): 521-532 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Sona Gregorová, Petr Divina, Radka Storchova, Zdenek Trachtulec, Vladana Fotopulosova, Karen L. Svenson, Leah Rae Donahue, Beverly Paigen, and Jiri Forejt
Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies
Genome Res. 2008; 18(3): 509-515 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Toyoyuki Takada, Akihiko Mita, Akiteru Maeno, Takahiro Sakai, Hiroshi Shitara, Yoshiaki Kikkawa, Kazuo Moriwaki, Hiromichi Yonekawa, and Toshihiko Shiroishi
Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits
Genome Res. 2008; 18(3): 500-508 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Julie E. Horvath, David W. Weisrock, Stephanie L. Embry, Isabella Fiorentino, James P. Balhoff, Peter Kappeler, Gregory A. Wray, Huntington F. Willard, and Anne D. Yoder
Development and application of a phylogenomic toolkit: Resolving the evolutionary history of Madagascar’s lemurs
Genome Res. 2008; 18(3): 489-499 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Saurabh Sinha, Adam S. Adler, Yair Field, Howard Y. Chang, and Eran Segal
Systematic functional characterization of cis-regulatory motifs in human core promoters
Genome Res. 2008; 18(3): 477-488 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Jon Reinders, Céline Delucinge Vivier, Grégory Theiler, Didier Chollet, Patrick Descombes, and Jerzy Paszkowski
Genome-wide, high-resolution DNA methylation profiling using bisulfite-mediated cytosine conversion
Genome Res. 2008; 18(3): 469-476 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Otto X. Cordero, Berend Snel, and Paulien Hogeweg
Coevolution of gene families in prokaryotes
Genome Res. 2008; 18(3): 462-468 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Malay Kumar Basu, Liran Carmel, Igor B. Rogozin, and Eugene V. Koonin
Evolution of protein domain promiscuity in eukaryotes
Genome Res. 2008; 18(3): 449-461 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Tomoyuki Kosaka, Souichiro Kato, Takefumi Shimoyama, Shunichi Ishii, Takashi Abe, and Kazuya Watanabe
The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota
Genome Res. 2008; 18(3): 442-448 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Christel Cazalet, Sophie Jarraud, Yad Ghavi-Helm, Frank Kunst, Philippe Glaser, Jerome Etienne, and Carmen Buchrieser
Multigenome analysis identifies a worldwide distributed epidemic Legionella pneumophila clone that emerged within a highly diverse species
Genome Res. 2008; 18(3): 431-441 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Tongming Yin, Stephen P. DiFazio, Lee E. Gunter, Xinye Zhang, Michell M. Sewell, Scott A. Woolbright, Gery J. Allan, Collin T. Kelleher, Carl J. Douglas, Mingxiu Wang, and Gerald A. Tuskan
Genome structure and emerging evidence of an incipient sex chromosome in Populus
Genome Res. 2008; 18(3): 422-430 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data] [Podcast]

Wenfeng Qian and Jianzhi Zhang
Evolutionary dynamics of nematode operons: Easy come, slow go
Genome Res. 2008; 18(3): 412-421 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Zhongmin Tian, Andrew S. Greene, Jennifer L. Pietrusz, Isaac R. Matus, and Mingyu Liang
MicroRNA–target pairs in the rat kidney identified by microRNA microarray, proteomic, and bioinformatic analysis
Genome Res. 2008; 18(3): 404-411 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

David S. Johnson, Wei Li, D. Benjamin Gordon, Arindam Bhattacharjee, Bo Curry, Jayati Ghosh, Leonardo Brizuela, Jason S. Carroll, Myles Brown, Paul Flicek, Christoph M. Koch, Ian Dunham, Mark Bieda, Xiaoqin Xu, Peggy J. Farnham, Philipp Kapranov, David A. Nix, Thomas R. Gingeras, Xinmin Zhang, Heather Holster, Nan Jiang, Roland D. Green, Jun S. Song, Scott A. McCuine, Elizabeth Anton, Loan Nguyen, Nathan D. Trinklein, Zhen Ye, Keith Ching, David Hawkins, Bing Ren, Peter C. Scacheri, Joel Rozowsky, Alexander Karpikov, Ghia Euskirchen, Sherman Weissman, Mark Gerstein, Michael Snyder, Annie Yang, Zarmik Moqtaderi, Heather Hirsch, Hennady P. Shulha, Yutao Fu, Zhiping Weng, Kevin Struhl, Richard M. Myers, Jason D. Lieb, and X. Shirley Liu
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets
Genome Res. 2008; 18(3): 393-403 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Reseach Data]

Alvaro Rada-Iglesias, Adam Ameur, Philipp Kapranov, Stefan Enroth, Jan Komorowski, Thomas R. Gingeras, and Claes Wadelius
Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders
Genome Res. 2008; 18(3): 380-392 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Eva Darai-Ramqvist, Agneta Sandlund, Stefan Müller, George Klein, Stefan Imreh, and Maria Kost-Alimova
Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions
Genome Res. 2008; 18(3): 370-379 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Xiang Gao, Yi Hou, Hirotaka Ebina, Henry L. Levin, and Daniel F. Voytas
Chromodomains direct integration of retrotransposons to heterochromatin
Genome Res. 2008; 18(3): 359-369 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Reseach Data] [Podcast]

Georgios S. Vernikos and Julian Parkhill
Resolving the structural features of genomic islands: A machine learning approach
Genome Res. 2008; 18(2): 331-342 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Thomas Abeel, Yvan Saeys, Eric Bonnet, Pierre Rouzé, and Yves Van de Peer
Generic eukaryotic core promoter prediction using structural features of DNA
Genome Res. 2008; 18(2): 310-323 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Gerton Lunter, Andrea Rocco, Naila Mimouni, Andreas Heger, Alexandre Caldeira, and Jotun Hein
Uncertainty in homology inferences: Assessing and improving genomic sequence alignment
Genome Res. 2008; 18(2): 298-309 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Victor Kunin, Shaomei He, Falk Warnecke, S. Brook Peterson, Hector Garcia Martin, Matthew Haynes, Natalia Ivanova, Linda L. Blackall, Mya Breitbart, Forest Rohwer, Katherine D. McMahon, and Philip Hugenholtz
A bacterial metapopulation adapts locally to phage predation despite global dispersal
Genome Res. 2008; 18(2): 293-297 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Tobias Mourier, Celine Carret, Sue Kyes, Zoe Christodoulou, Paul P. Gardner, Daniel C. Jeffares, Robert Pinches, Bart Barrell, Matt Berriman, Sam Griffiths-Jones, Alasdair Ivens, Chris Newbold, and Arnab Pain
Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum
Genome Res. 2008; 18(2): 281-292 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Naruo Nikoh, Kohjiro Tanaka, Fukashi Shibata, Natsuko Kondo, Masahiro Hizume, Masakazu Shimada, and Takema Fukatsu
Wolbachia genome integrated in an insect chromosome: Evolution and fate of laterally transferred endosymbiont genes
Genome Res. 2008; 18(2): 272-280 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Heiko Schober, Véronique Kalck, Miguel A. Vega-Palas, Griet Van Houwe, Daniel Sage, Michael Unser, Marc R. Gartenberg, and Susan M. Gasser
Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast
Genome Res. 2008; 18(2): 261-271 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

David M. McGaughey, Ryan M. Vinton, Jimmy Huynh, Amr Al-Saif, Michael A. Beer, and Andrew S. McCallion
Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b
Genome Res. 2008; 18(2): 252-260 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Elfar Torarinsson, Zizhen Yao, Eric D. Wiklund, Jesper B. Bramsen, Claus Hansen, Jørgen Kjems, Niels Tommerup, Walter L. Ruzzo, and Jan Gorodkin
Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions
Genome Res. 2008; 18(2): 242-251 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Zhuo Du, Yiqiang Zhao, and Ning Li
Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription
Genome Res. 2008; 18(2): 233-241 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Anuphap Prachumwat and Wen-Hsiung Li
Gene number expansion and contraction in vertebrate genomes with respect to invertebrate genomes
Genome Res. 2008; 18(2): 221-232 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Amir Goren, Eddo Kim, Maayan Amit, Ron Bochner, Galit Lev-Maor, Nadav Ahituv, and Gil Ast
Alternative approach to a heavy weight problem
Genome Res. 2008; 18(2): 214-220 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Lixia Yao and Andrey Rzhetsky
Quantitative systems-level determinants of human genes targeted by successful drugs
Genome Res. 2008; 18(2): 206-213 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data] [Podcast]

Brandi L. Cantarel, Ian Korf, Sofia M.C. Robb, Genis Parra, Eric Ross, Barry Moore, Carson Holt, Alejandro Sánchez Alvarado, and Mark Yandell
MAKER: An easy-to-use annotation pipeline designed for emerging model organism genomes
Genome Res. 2008; 18(1): 188-196 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Xiangjun Du, Zhuo Wang, Aiping Wu, Lin Song, Yang Cao, Haiying Hang, and Taijiao Jiang
Networks of genomic co-occurrence capture characteristics of human influenza A (H3N2) evolution
Genome Res. 2008; 18(1): 178-187 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Tatiana Teixeira Torres, Muralidhar Metta, Birgit Ottenwälder, and Christian Schlötterer
Gene expression profiling by massively parallel sequencing
Genome Res. 2008; 18(1): 172-177 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Nicholas R. Thomson, Matthew T.G. Holden, Caroline Carder, Nicola Lennard, Sarah J. Lockey, Pete Marsh, Paul Skipp, C. David O’Connor, Ian Goodhead, Halina Norbertzcak, Barbara Harris, Doug Ormond, Richard Rance, Michael A. Quail, Julian Parkhill, Richard S. Stephens, and Ian N. Clarke
Chlamydia trachomatis: Genome sequence analysis of lymphogranuloma venereum isolates
Genome Res. 2008; 18(1): 161-171 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Nacho Molina and Erik van Nimwegen
Universal patterns of purifying selection at noncoding positions in bacteria
Genome Res. 2008; 18(1): 148-160 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Devin R. Scannell and Kenneth H. Wolfe
A burst of protein sequence evolution and a prolonged period of asymmetric evolution follow gene duplication in yeast
Genome Res. 2008; 18(1): 137-147 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Jian Chen, Xiaoying Shi, Ranjani Padmanabhan, Qiong Wang, Zhidan Wu, Susan C. Stevenson, Marc Hild, Dan Garza, and Hao Li
Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster
Genome Res. 2008; 18(1): 123-136 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Bin Li, Reinhard Predel, Susanne Neupert, Frank Hauser, Yoshiaki Tanaka, Giuseppe Cazzamali, Michael Williamson, Yasuyuki Arakane, Peter Verleyen, Liliane Schoofs, Joachim Schachtner, Cornelis J.P. Grimmelikhuijzen, and Yoonseong Park
Genomics, transcriptomics, and peptidomics of neuropeptides and protein hormones in the red flour beetle Tribolium castaneum
Genome Res. 2008; 18(1): 113-122 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Guo-Qing Tang and E. Stuart Maxwell
Xenopus microRNA genes are predominantly located within introns and are differentially expressed in adult frog tissues via post-transcriptional regulation
Genome Res. 2008; 18(1): 104-112 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Schraga Schwartz, João Silva, David Burstein, Tal Pupko, Eduardo Eyras, and Gil Ast
Large-scale comparative analysis of splicing signals and their corresponding splicing factors in eukaryotes
Genome Res. 2008; 18(1): 88-103 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Xavier Roca, Andrew J. Olson, Atmakuri R. Rao, Espen Enerly, Vessela N. Kristensen, Anne-Lise Børresen-Dale, Brage S. Andresen, Adrian R. Krainer, and Ravi Sachidanandam
Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics
Genome Res. 2008; 18(1): 77-87 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Katherine C. Teeter, Bret A. Payseur, Leslie W. Harris, Margaret A. Bakewell, Lisa M. Thibodeau, Janelle E. O’Brien, James G. Krenz, Maria A. Sans-Fuentes, Michael W. Nachman, and Priscilla K. Tucker
Genome-wide patterns of gene flow across a house mouse hybrid zone
Genome Res. 2008; 18(1): 67-76 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Leah O. Barrera, Zirong Li, Andrew D. Smith, Karen C. Arden, Webster K. Cavenee, Michael Q. Zhang, Roland D. Green, and Bing Ren
Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs
Genome Res. 2008; 18(1): 46-59 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Yogeshwar D. Kelkar, Svitlana Tyekucheva, Francesca Chiaromonte, and Kateryna D. Makova
The genome-wide determinants of human and chimpanzee microsatellite evolution
Genome Res. 2008; 18(1): 30-38 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Yulia Korshunova, Rebecca K. Maloney, Nathan Lakey, Robert W. Citek, Blaire Bacher, Arief Budiman, Jared M. Ordway, W. Richard McCombie, Jorge Leon, Jeffrey A. Jeddeloh, and John D. McPherson
Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA
Genome Res. 2008; 18(1): 19-29 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Dawn M. Stults, Michael W. Killen, Heather H. Pierce, and Andrew J. Pierce
Genomic architecture and inheritance of human ribosomal RNA gene clusters
Genome Res. 2008; 18(1): 13-18 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Martin C. Frith, Eivind Valen, Anders Krogh, Yoshihide Hayashizaki, Piero Carninci, and Albin Sandelin
A code for transcription initiation in mammalian genomes
Genome Res. 2008; 18(1): 1-12 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]


Genome Res. 2008; 18(1): 1-197  
Issue supplement(s): [Cover Caption Erratum]

Matthew D. Rasmussen and Manolis Kellis
Accurate gene-tree reconstruction by learning gene- and species-specific substitution rates across multiple complete genomes
Genome Res. 2007; 17(12): 1932-1942 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Pouya Kheradpour, Alexander Stark, Sushmita Roy, and Manolis Kellis
Reliable prediction of regulator targets using 12 Drosophila genomes
Genome Res. 2007; 17(12): 1919-1931 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Alfredo Villasante, José P. Abad, Rosario Planelló, María Méndez-Lago, Susan E. Celniker, and Beatriz de Pablos
Drosophila telomeric retrotransposons derived from an ancestral element that was recruited to replace telomerase
Genome Res. 2007; 17(12): 1909-1918 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Pär G. Engström, Shannan J. Ho Sui, Øyvind Drivenes, Thomas S. Becker, and Boris Lenhard
Genomic regulatory blocks underlie extensive microsynteny conservation in insects
Genome Res. 2007; 17(12): 1898-1908 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Deborah E. Stage and Thomas H. Eickbush
Sequence variation within the rRNA gene loci of 12 Drosophila species
Genome Res. 2007; 17(12): 1888-1897 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Arjun Bhutkar, Susan M. Russo, Temple F. Smith, and William M. Gelbart
Genome-scale analysis of positionally relocated genes
Genome Res. 2007; 17(12): 1880-1887 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Alexander Stark, Pouya Kheradpour, Leopold Parts, Julius Brennecke, Emily Hodges, Gregory J. Hannon, and Manolis Kellis
Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
Genome Res. 2007; 17(12): 1865-1879 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

J. Graham Ruby, Alexander Stark, Wendy K. Johnston, Manolis Kellis, David P. Bartel, and Eric C. Lai
Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
Genome Res. 2007; 17(12): 1850-1864 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Andreas Heger and Chris P. Ponting
Evolutionary rate analyses of orthologs and paralogs from 12 Drosophila genomes
Genome Res. 2007; 17(12): 1837-1849 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Michael F. Lin, Joseph W. Carlson, Madeline A. Crosby, Beverley B. Matthews, Charles Yu, Soo Park, Kenneth H. Wan, Andrew J. Schroeder, L. Sian Gramates, Susan E. St. Pierre, Margaret Roark, Kenneth L. Wiley Jr., Rob J. Kulathinal, Peili Zhang, Kyl V. Myrick, Jerry V. Antone, Susan E. Celniker, William M. Gelbart, and Manolis Kellis
Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes
Genome Res. 2007; 17(12): 1823-1836 [Abstract] [Full Text]  
Article supplement(s): [Drosophila 12 Genomes] [Supplemental Research Data]

Michael J. Cornell, Intikhab Alam, Darren M. Soanes, Han Min Wong, Cornelia Hedeler, Norman W. Paton, Magnus Rattray, Simon J. Hubbard, Nicholas J. Talbot, and Stephen G. Oliver
Comparative genome analysis across a kingdom of eukaryotic organisms: Specialization and diversification in the Fungi
Genome Res. 2007; 17(12): 1809-1822 [Abstract] [Full Text]  
Article supplement(s): [HTML Page - index.htslp]

Webb Miller, Kate Rosenbloom, Ross C. Hardison, Minmei Hou, James Taylor, Brian Raney, Richard Burhans, David C. King, Robert Baertsch, Daniel Blankenberg, Sergei L. Kosakovsky Pond, Anton Nekrutenko, Belinda Giardine, Robert S. Harris, Svitlana Tyekucheva, Mark Diekhans, Thomas H. Pringle, William J. Murphy, Arthur Lesk, George M. Weinstock, Kerstin Lindblad-Toh, Richard A. Gibbs, Eric S. Lander, Adam Siepel, David Haussler, and W. James Kent
28-Way vertebrate alignment and conservation track in the UCSC Genome Browser
Genome Res. 2007; 17(12): 1797-1808 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Matthieu Legendre, Nathalie Pochet, Theodore Pak, and Kevin J. Verstrepen
Sequence-based estimation of minisatellite and microsatellite repeat variability
Genome Res. 2007; 17(12): 1787-1796 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Bernhard Suter, Michael J. Fetchko, Ralph Imhof, Christopher I. Graham, Ingrid Stoffel-Studer, Caroline Zbinden, Maanasa Raghavan, Lianet Lopez, Lucija Beneti, Jacqueline Hort, Jeffrey Fillingham, Jack F. Greenblatt, Guri Giaever, Corey Nislow, and Igor Stagljar
Examining protein–protein interactions using endogenously tagged yeast arrays: The Cross-and-Capture system
Genome Res. 2007; 17(12): 1774-1782 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Adam Siepel, Mark Diekhans, Brona Brejová, Laura Langton, Michael Stevens, Charles L.G. Comstock, Colleen Davis, Brent Ewing, Shelly Oommen, Christopher Lau, Hung-Chun Yu, Jianfeng Li, Bruce A. Roe, Phil Green, Daniela S. Gerhard, Gary Temple, David Haussler, and Michael R. Brent
Targeted discovery of novel human exons by comparative genomics
Genome Res. 2007; 17(12): 1763-1773 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Peter Andolfatto
Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome
Genome Res. 2007; 17(12): 1755-1762 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Gene Cutler, Lisa A. Marshall, Ni Chin, Helene Baribault, and Paul D. Kassner
Significant gene content variation characterizes the genomes of inbred mouse strains
Genome Res. 2007; 17(12): 1743-1754 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Kee-Pyo Kim, Alexandra Thurston, Christine Mummery, Dorien Ward-van Oostwaard, Helen Priddle, Cinzia Allegrucci, Chris Denning, and Lorraine Young
Gene-specific vulnerability to imprinting variability in human embryonic stem cell lines
Genome Res. 2007; 17(12): 1731-1742 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Philippe P. Luedi, Fred S. Dietrich, Jennifer R. Weidman, Jason M. Bosko, Randy L. Jirtle, and Alexander J. Hartemink
Computational and experimental identification of novel human imprinted genes
Genome Res. 2007; 17(12): 1723-1730 [Abstract] [Full Text]  
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Christiane Robbins, Jada Benn Torres, Stanley Hooker, Carolina Bonilla, Wenndy Hernandez, Angela Candreva, Chiledum Ahaghotu, Rick Kittles, and John Carpten
Confirmation study of prostate cancer risk variants at 8q24 in African Americans identifies a novel risk locus
Genome Res. 2007; 17(12): 1717-1722 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Juliane C. Dohm, Claudio Lottaz, Tatiana Borodina, and Heinz Himmelbauer
SHARCGS, a fast and highly accurate short-read assembly algorithm for de novo genomic sequencing
Genome Res. 2007; 17(11): 1697-1706 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Robert Lyle, Paola Prandini, Kazutoyo Osoegawa, Boudewijn ten Hallers, Sean Humphray, Baoli Zhu, Eduardo Eyras, Robert Castelo, Christine P. Bird, Sarantos Gagos, Carol Scott, Antony Cox, Samuel Deutsch, Catherine Ucla, Marc Cruts, Sophie Dahoun, Xinwei She, Frederique Bena, Sheng-Yue Wang, Christine Van Broeckhoven, Evan E. Eichler, Roderic Guigo, Jane Rogers, Pieter J. de Jong, Alexandre Reymond, and Stylianos E. Antonarakis
Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21
Genome Res. 2007; 17(11): 1690-1696 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Joan U. Pontius, James C. Mullikin, Douglas R. Smith, Agencourt Sequencing Team, Kerstin Lindblad-Toh, Sante Gnerre, Michele Clamp, Jean Chang, Robert Stephens, Beena Neelam, Natalia Volfovsky, Alejandro A. Schäffer, Richa Agarwala, Kristina Narfström, William J. Murphy, Urs Giger, Alfred L. Roca, Agostinho Antunes, Marilyn Menotti-Raymond, Naoya Yuhki, Jill Pecon-Slattery, Warren E. Johnson, Guillaume Bourque, Glenn Tesler, NISC Comparative Sequencing Program, and Stephen J. O’Brien
Initial sequence and comparative analysis of the cat genome
Genome Res. 2007; 17(11): 1675-1689 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Kai Wang, Mingyao Li, Dexter Hadley, Rui Liu, Joseph Glessner, Struan F.A. Grant, Hakon Hakonarson, and Maja Bucan
PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
Genome Res. 2007; 17(11): 1665-1674 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Guillaume Blanc, Hiroyuki Ogata, Catherine Robert, Stéphane Audic, Jean-Michel Claverie, and Didier Raoult
Lateral gene transfer between obligate intracellular bacteria: Evidence from the Rickettsia massiliae genome
Genome Res. 2007; 17(11): 1657-1664 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Thierry Wirth, Giovanna Morelli, Barica Kusecek, Alex van Belkum, Cindy van der Schee, Axel Meyer, and Mark Achtman
The rise and spread of a new pathogen: Seroresistant Moraxella catarrhalis
Genome Res. 2007; 17(11): 1647-1656 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Marius K. Lemberg and Matthew Freeman
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases
Genome Res. 2007; 17(11): 1634-1646 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Tomer Shlomi, Markus Herrgard, Vasiliy Portnoy, Efrat Naim, Bernhard Ø. Palsson, Roded Sharan, and Eytan Ruppin
Systematic condition-dependent annotation of metabolic genes
Genome Res. 2007; 17(11): 1626-1633 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Shisong Ma, Qingqiu Gong, and Hans J. Bohnert
An Arabidopsis gene network based on the graphical Gaussian model
Genome Res. 2007; 17(11): 1614-1625 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Laurie Gordon, Shan Yang, Mary Tran-Gyamfi, Dan Baggott, Mari Christensen, Aaron Hamilton, Richard Crooijmans, Martien Groenen, Susan Lucas, Ivan Ovcharenko, and Lisa Stubbs
Comparative analysis of chicken chromosome 28 provides new clues to the evolutionary fragility of gene-rich vertebrate regions
Genome Res. 2007; 17(11): 1603-1613 [Abstract] [Full Text]  
Article supplement(s): [Supplemental Research Data]

Chris Wallace, Richard J. Dobson, Patricia B. Munroe, and Mark J. Caulfield
Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates
Genome Res. 2007; 17(11): 1596-1602